Varicella. Clinical Manifestations

PRIMARY INFECTION Primary infection with VZV produces the well-known clinical syndrome of varicella or chickenpox. Low-grade fever may precede the development of the rash by 1 to 2 days. The characteristic rash involves lesions that appear in crops and proceed

Varicella zoster virus

Varicella zoster virus (VZV) causes varicella, the most common exanthematous disease of childhood. After the acute infection, VZV remains latent in the dorsal root ganglia; reactivation of the virus later in life causes zoster. VZV is ubiquitous, and humans are

Embryo Reduction. Management

Management Antenatal management should include attention to nutrition, avoidance of strenuous physical activity, frequent prenatal visits, and counseling on symptoms of preterm labor, PROM, and hypertensive disorders of pregnancy. Ultrasound assessment of fetal growth and amniotic fluid volume should be

Multiple Gestation

Multiple gestation occurs in about 1.5% of all births. Multiple pregnancies of greater than three constitute a relatively small component of the total; however, these numbers are increasing as a result of the widespread use of assisted reproductive technologies. Twins

Congenital Infections. Conclusion

The diagnosis; a lot is written both in diagnosis and treatment and it always changes, but I think with syphilis you have to have some common sense and know your patient and know what the future is and whether you

Parvovirus B19

Next is parvovirus B19. The infection in pregnant women results in infection of the fetus and the timing of that depends a bit on what happens. But in the first half of pregnancy you get red cell aplasia and it

Treatment for Congenital Infections

As far as treatment … I should go back. I realize I didn’t say anything about treatment with CMV and the babies with congenital CMV; you would like to treat them and with recent successes with toxoplasmosis it makes this

Herpes and congenital infection

Next is herpes and this is a newspaper from right after acyclovir was first licensed. The main situation with herpes is that the congenital infection is only a small part. The major problem with herpes is acquisition of virus infection

Rubella

Okay, now to switch over to rubella. This is something that we really shouldn’t need to talk about today. Rubella should be gone, and yet there are a number of young adults who weren’t vaccinated and who have been protected

Hepatomegaly, splenomegaly

The clinical manifestations are listed here; hepatomegaly, splenomegaly, hyperbilirubinemia. Generalized diffuse infection with CMV virus; the various manifestations you see here; cerebral calcifications. A big deal is made by the difference of these calcifications and toxoplasmosis, and it’s a good

Congenital Infections

Pregnant women have a lot of infections and fortunately only a few of those affect the fetus. A number of years ago – actually many many years ago – we did a study and just in a six week period

Treatment for autism

FENFLURAMINE The finding of hyperserotonemia in one third of autistic children led to the hypothesis that autistic symptoms may be due to increased brain serotonin levels. That hypothesis in turn led to the study of fenfluramine, a serotonin depleter, in