Monthly Archives: December 2008

Genetic factors. Autism

Results of family and twin studies have established the likelihood that genetic factors may influence or contribute to the development of autism. Three twin studies comparing concordance rates for autism in monozygotic and same-sex dizygotic twin pairs found concordance rates


Autistic disorder is the best known of the pervasive developmental disorders. It is characterized by sustained impairments in reciprocal social interactions, communication deviance, and restricted, stereotypical behavioral patterns. According to DSM-IV, abnormal functioning in the above areas must be present

Pelvic inflammatory disease

With females, there is cervicitis, discharge and an inflamed, nontender cervix. Spread can occur to the rectum, which is usually totally asymptomatic. Then spread can occur beyond the mucosa of the urethra, of the cervix, of the rectum and of

Gonorrhea is a disease of the young

Gonorrhea is a disease of the young – 15 to 25 years as defined by the CDC. It is more common in urban blacks of low socioeconomic status. This is somewhat interesting. We see a lot more gonorrhea in people


Gonorrhea and Chlamydia As we have learned more and more about chlamydia, we have come to recognize that gonorrhea and chlamydia are not only often transmitted together but also very, very difficult to differentiate in terms of the syndromes they

Some directions for future research

Okay, some directions for future research here. We are interested in looking at how fibromyalgia patients perform when they are distracted. We call this “dividing attention” where they have to do two things at once. And we think given their

Pincus Cognitive Symptoms Inventory

What about memory complaints? We use the Pincus Cognitive Symptoms Inventory, which is simply ask patients what they complain about with respect to their memory. What are their problems? We also have a longer more elaborate cognitive inventory called the

Verbal fluency

Verbal fluency, also another highly frontal task in terms of cortex. This is, to remind you, where subjects are given a letter like F and told to produce as many words as they can think of that begin with the

The data on cognitive function

Now I’d like to turn to the data on cognitive function. The first data that I am going to show you is this speed of processing task. As I mentioned to you, we see speed of processing as fundamental to

In terms of pain

This is what performance on these tests look like. Across, a sample of older, of adults age 20-90. And you can see that performance, regrettably for all of us in this room, begins declining in your 20’s and all the